Tom Cavanagh...Mal Downey/Jerry

Sarah Chalke...Samantha Rose

James Barbour...Dr. Troy Rollins

Nadia Dajani...Jane

Illeana Douglas...KJ

Logan Marshall-Green...Martin

Celeste Holm...Iris

Anna Belknap...Marissa

Tovah Feldshuh...Associate Editor

Daphne Rubin-Vega...Editor

Ajay Naidu...Best Man

Erik Palladino...Groom